Article
Eleven trinucleotide repeat loci that map to chromosome 12 excluded from involvement in the pathogenesis of bipolar disorder.
American journal of medical genetics - 5 Feb 1999
Franks E, Guy C, Jacobsen N, Bowen T, Owen M J, O'Donovan M C, Craddock N
Abstract excerpt
The hypothesis that one or more genes containing expanded trinucleotide repeats contribute to the pathogenesis of bipolar disorder has received support from three independent studies demonstrating that bipolar patients tend to have larger CAG/CTG repeat expansion detection products than controls. In an attempt to identify the specific expanded CAG/CTG locus or loci which are associated with bipolar disorder, we...
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