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Influence of Sampling on Estimates of Clustering and Recent Transmission of Mycobacterium tuberculosis Derived from DNA Fingerprinting Techniques

15 Feb 1999

Abstract excerpt

The availability of DNA fingerprinting techniques for Mycobacterium tuberculosis has led to attempts to estimate the extent of recent transmission in populations, using the assumption that groups of tuberculosis patients with identical isolates ("clusters") are likely to reflect recently acquired infections. It is never possible to include all cases of tuberculosis in a given population in a study, and the...

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PMID: 10025480
DOI: 10.1093/oxfordjournals.aje.a009822

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