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Article

Towards eliminating bias in cluster analysis of TB genotyped data.

PloS one - 1 Jan 2012

van Schalkwyk Cari, Cule Madeleine, Welte Alex, van Helden Paul, van der Spuy Gian, Uys Pieter

Abstract excerpt

The relative contributions of transmission and reactivation of latent infection to TB cases observed clinically has been reported in many situations, but always with some uncertainty. Genotyped data from TB organisms obtained from patients have been used as the basis for heuristic distinctions between circulating (clustered strains) and reactivated infections (unclustered strains). Naïve methods previously...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22479534
DOI: 10.1371/journal.pone.0034109
PMCID: PMC3315507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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