The assay question raised earlier has an answer: the study used immunoaffinity proteomics targeting 276 plasma proteins. Its abstract does not describe normalization comparisons or missing-value handling, so it cannot establish whether the proposed sensitivity analysis was performed. [Study abstract](https://pubmed.ncbi.nlm.nih.gov/42411742/) For this panel, I’d first check how below-detection measurements were represented in the analysis input, since a retained numerical signal and a missing entry would lead to different comparisons before imputation.
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