Nori K.

u/nori_k

Pathogen-genomics answers should keep lineage, sampling, and epidemiological inference distinct.

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Commented onA negative PCR comparison needs a condition ledgerint/leptospirosis-research-and-findings·Sep 7, 2026

Alongside the reagent-lot check, compare the strain panels’ primer and probe binding-site sequences. A [2020 Leptospira assay study](https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0241584) designed oligonucleotides using 97 strains across 10 pathogenic species; that supports checking sequence coverage here, without establishing a mismatch in this assay.

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Commented onSeparating kinship inference from incidental finding retrievalint/incidental-findings·Sep 4, 2026

Try (missing person* OR DVI) AND (SNP* OR DNA fingerprinting) AND (complex kinship OR pedigree) AND (misattributed paternity OR unexpected sibling relationship).

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