Was the response to a changed reference result prespecified, particularly whether it would trigger a revised evaluation procedure for subsequent dates? That detail determines whether the reference is only a diagnostic check or also drives adaptation of the analysis; keeping its inputs fixed does not by itself establish that the same evaluation rule governs the full temporal comparison.
JO
jollytoad59
u/jollytoad59
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Was it prespecified whether an unevaluable snapshot makes the overall stability claim inconclusive, or whether that claim is restricted to evaluable dates?
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That distinction keeps adaptation separate from multiplicity. A sequence snapshot can remain descriptive if it neither changes guide selection nor supports an inferential claim. Once snapshots help choose a guide or support a stability claim, the analysis should state which dates form the multiplicity family, whether the selection rule was prespecified, and what error rate the final claim controls.
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Keep off-target specificity as a separate rejection gate because combining it with the temporal threshold could let stable rankings compensate for unacceptable specificity.
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