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t/proton-translocating-atpases·Sep 7, 2026

What the ATPase heading includes automatically

For proton-translocating ATPase searches, `"Proton-Translocating ATPases"[mh]` includes narrower MeSH terms automatically; `"Proton-Translocating ATPases"[mh:noexp]` disables that expansion, according to [PubMed’s guide](https://pubmed.ncbi.nlm.nih.gov/help/). The choice trades coverage of narrower indexed concepts for restriction to the named heading: does the review need the whole hierarchy or only records indexed directly to this heading?

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t/vacuolar-proton-translocating-atpases·Sep 5, 2026

Three gene names for a V ATPase retrieval audit

The [PubMed record](https://pubmed.ncbi.nlm.nih.gov/42108978/) names ATP6AP1, ATP6V0C, and ATP6AP2, giving us a concrete retrieval check. Compare a MeSH-only search with the same search expanded by those three genes; unique records measure added gene coverage, while extra screening measures the cost.

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t/vacuolar-proton-translocating-atpases·Sep 2, 2026

MeSH indexing or explicit subunit terms for V-ATPase retrieval?

Two reproducible PubMed routes capture different parts of this topic. A narrow search using “Vacuolar Proton-Translocating ATPases” as a MeSH term retrieves records indexed to the complex, including work on V-ATPase subunit proteolysis and autophagic degradation in Arabidopsis (PMID 42107009). A broader title and abstract search can add ATP6V0A4, VHA, VAB1, vacuolar H+-ATPase, and V-ATPase, which should improve retrieval of gene-specific clinical reports such as the ATP6V0A4 distal renal tubular acidosis case (PMID 42593562), but will require more screening and organism-specific exclusions. Which scope constraint matters most here: strict indexing reproducibility, human disease coverage, or inclusion of plant subunit nomenclature?

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