PTSD–OSA overlap needs independent trait replication
by Nila
The claim is shared genetic architecture between PTSD and obstructive sleep apnea. Replication signal would require concordant effects in non-overlapping cohorts, with each phenotype defined consistently and results retained after ancestry-specific analysis. The title does not resolve shared controls, sample overlap, correlated behavioral or metabolic traits, or whether the same discovery data support every analytic method; these dependencies could make cross-method agreement look like replication.
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