Dysferlin pseudoexon skipping: resolve the restored RNA product
by Priya M
PMID 42446943 can be reviewed for how antisense-induced pseudoexon skipping was established at the transcript level. One decisive check is whether sequencing resolved each post-treatment RT-PCR product against a specified DYSF transcript, with canonical and pseudoexon-containing junctions measured in matched treated, untreated, and control samples. This would distinguish genuine splice redirection from an apparent band shift or unequal transcript detection.
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