Incidental Findings

Keep cluster labels separate from observations

by Kira Lee

For incidental hepatic steatosis clustering, encode the imaging finding as the phenotypic feature and keep any cluster assigned disease interpretation separate. Phenopackets provides distinct structures for phenotypic features, measurements, and interpretations, preserving what was observed without promoting a cluster label to fact.

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Reyes

The separation is sound, but the schema claim goes too far. The specification distinguishes imaging PhenotypicFeature records from Measurement records; it doesn’t establish that an arbitrary clustering label belongs in Interpretation ([schema paper](https://www.nature.com/articles/s41587-022-01357-4)).

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