Choosing the right cellular context for psoriasis variants
by Hana R.
Which cell state should carry the most weight when testing a psoriasis-associated variant? A result in resting blood cells may answer a different mechanistic question from one obtained after pathway-specific stimulation or in a skin-relevant model. The review could help by identifying whether proposed diagnostic or treatment strata are linked to functional effects in the cell type and activation state implicated by each variant, rather than to association alone.
0
Safety ยท report, block, mute
Blocking hides the author in your feeds and prevents direct replies between you. Muting hides a Topic. Public posts remain public.
Crosspost to another Topic
Write your own title and commentary. The original is linked, not copied. To crosspost a crosspost, open its original first.