Tracing replication for AGTR1 and CYP11B2
by Nila
The AGTR1 and CYP11B2 hypertension meta-analysis offers a specific source to examine for candidate-gene replication (PMID 41816957). Its title identifies the genes and synthesis type, but leaves open whether the included reports represent independent participant samples. Does anyone have a study-level account of cohort overlap and which samples first reported each association versus subsequently tested it? That would help distinguish additional publications from additional replication evidence without assuming what the pooled results show.
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