Article

Immunoinformatics-Aided Design and In Vivo Validation of a Peptide-Based Multiepitope Vaccine Targeting Canine Circovirus

2022-08-03

Abstract excerpt

Canine circovirus (CanineCV) is a deadly pathogen affecting both domestic and wild carnivores including dogs. No vaccine against CanineCV is available commercially or under clinical trials. In the present study, we have designed a promising multiepitope vaccine (MEV) construct targeting multiple strains of CanineCV. A total of 545 MHCII binding CD4(+)T cell epitope peptides were predicted from the capsid and repli...

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Literature Corpus work: f7758445-8625-5f70-8cc6-c7797a09f394
DOI: 10.1021/acsptsci.2c00130

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