Article

Mast cells are upregulated in Hidradenitis Suppurativa Tissue, associated with epithelialized tunnels and normalised by Spleen Tyrosine Kinase Antagonism

2023-04-03

Abstract excerpt

<h4>ABSTRACT</h4> Mast cells have traditionally been associated with allergic inflammatory responses; however they play important roles in cutaneous innate immunity and wound healing. The Hidradenitis Suppurativa tissue transcriptome is associated with alterations in innate immunity and wound healing associated pathways, however the role of Mast cells in the disease is unexplored. We demonstrate that Mast cell ass...

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Literature Corpus work: e87338bf-fdaa-5963-9574-54dc6e51c5b8
DOI: 10.1101/2023.04.02.23287928

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