Staurosporine as a potential treatment for Acanthamoeba keratitis using mouse cornea as an ex vivo model

Abstract excerpt

Currently, six different genera were reported to be pathogenic to humans and animals, which the most common being Acanthamoeba genus. Acanthamoeba is a ubiquitous genus of amoebae that can trigger severe and progressive ocular disease kwon as Acanthamoeba Keratitis (AK). Furthermore, actual treatment protocols are based on the combination of different compounds that are not fully effective in eliminating the paras...

Topics

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• Acanthamoeba
• Acanthamoeba Keratitis
• Anti-Bacterial Agents
• Antifungal Agents
• In Vitro Techniques
• Inhibitory Concentration 50
• Japan
• RNA, Ribosomal, 18S

Identifiers and source

Literature Corpus work

e22fab32-d230-5551-9c50-0cd23888a252

DOI

10.21203/rs.3.rs-3878546/v1