Article
CPG Oligonucleotides as Vaccine Adjuvants for Prevention of Infectious Diseases
2024-09-01
Abstract excerpt
Abstract Synthetic oligonucleotides containing unmethylated CpG motifs activate the innate immune system by binding to cells expressing Toll-like receptor 9. In humans, these include plasmacytoid dendritic cells and B cells. Research results show that CpG oligonucleotides enhance humoral and cellular immune responses, as well as accelerate the induction of specific immunoglobulins and promote the formation of high...
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Identifiers and source
- Literature Corpus work
- bc9256f8-3b24-5648-87cb-f895e8390eac
- DOI
- 10.3103/s0891416824700253
