Article

Expression Profile of Cell Cycle-related Genes in Human Fibroblasts Exposed Simultaneously to Radiation and Simulated Microgravity

2019-06-03

Abstract excerpt

Multiple unique environmental factors such as space radiation and microgravity (µG) pose a serious threat to human gene stability during space travel. Recently, we reported that simultaneous exposure of human fibroblasts to simulated µG and radiation results in more chromosomal aberrations than in cells exposed to radiation alone. However, the mechanisms behind this remain unknown. The purpose of this...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ab0f1a53-9a79-575b-95e5-045f28936415
DOI: 10.20944/preprints201906.0021.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Expression Profile of Cell Cycle-related Genes in Human Fibroblasts Exposed Simultaneously to Radiation and Simulated MicrogravityDOI 10.20944/preprints201906.0021.v1Read

Increased Chromosome Aberrations in Cells Exposed Simultaneously to Simulated Microgravity and RadiationSemantic proximity Read

Simultaneous Exposure of Cultured Human Lymphoblastic Cells to Simulated Microgravity and Radiation Increases Chromosome AberrationsSemantic proximity Read

Cellular responses and gene expression profile changes due to bleomycin-induced DNA damage in human fibroblasts in spaceSemantic proximity Read

Genomic Changes Driven by Radiation-Induced DNA Damage and Microgravity in Human CellsSemantic proximity Read

Microgravity, Stem Cells, and Cancer: A New Hope for Cancer TreatmentSemantic proximity Read

Single-Cell RNA-Sequencing Identifies Activation of TP53 and STAT1 Pathways in Human T Lymphocyte Subpopulations in Response to Ex Vivo Radiation ExposureSemantic proximity Read

The Influence of Microgravity on Repair of Radiation-Induced DNA Damage in Bacteria and Human FibroblastsSemantic proximity Read

Genome Wide Expression Profiling of Cancer Cell Lines Cultured in Microgravity Reveals Significant Dysregulation of Cell Cycle and MicroRNA Gene NetworksSemantic proximity Read

Interplay of space radiation and microgravity in DNA damage and DNA damage responseSemantic proximity Read

A Study of Alterations in DNA Epigenetic Modifications (5mC and 5hmC) and Gene Expression Influenced by Simulated Microgravity in Human Lymphoblastoid CellsSemantic proximity Read

Omics Studies of Tumor Cells under Microgravity ConditionsSemantic proximity Read

Cancer Studies under Space Conditions: Finding Answers AbroadSemantic proximity Read