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Cellular responses and gene expression profile changes due to bleomycin-induced DNA damage in human fibroblasts in space

1 Mar 2017

Abstract excerpt

Living organisms in space are constantly exposed to radiation, toxic chemicals or reactive oxygen species generated due to increased levels of environmental and psychological stresses. Understanding the impact of spaceflight factors, microgravity in particular, on cellular responses to DNA damage is essential for assessing the radiation risk for astronauts and the mutation rate in microorganisms. In a study...

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PMID: 28248986
DOI: 10.1371/journal.pone.0170358

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