Exploration of the Noncoding Genome for Human-Specific Therapeutic Targets – Recent Insights at Molecular and Cellular Level

Abstract excerpt

While it is well known that 98-99% of the human genome do not encode proteins, but are nevertheless transcriptionally active and give rise to a broad spectrum of noncoding RNAs (ncRNAs) with complex regulatory and structural functions, specific functions have so far been assigned to only a tiny fraction of all known transcripts. On the other hand, the striking observation of an overwhelmingly growing fraction of n...

Topics

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• Disease
• Gene Expression
• Genetic Predisposition to Disease
• Genome, Human
• Models, Genetic
• RNA
• RNA, Mitochondrial
• RNA, Untranslated

Identifiers and source

Literature Corpus work

80d53742-866d-566f-910f-7f2ec83fca6d

DOI

10.20944/preprints202310.0414.v1