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Loci on chromosome 12q13.2 encompassing <i>ERBB3, PA2G4</i> and <i>RAB5B</i> are associated with polycystic ovary syndrome

2022-05-14

Abstract excerpt

Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenemia of ovarian theca cell origin. Here we report the significant association of 15 single nucleotide polymorphisms (SNPs), identified by whole exome sequencing (WES). DNA was isolated from well-characterized theca cell preparations from women of European ancestry with PCOS (N=9) and elevated androgen production in vitro and from normal ovulatory wo...

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Literature Corpus work
669fbf8e-2024-555c-97cc-f40464ddadbd
DOI
10.1101/2022.05.10.22274861
Open publication

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Loci on chromosome 12q13.2 encompassing <i>ERBB3, PA2G4</i> and <i>RAB5B</i> are associated with polycystic ovary syndromeDOI 10.1101/2022.05.10.22274861
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