Article

Role of Inflammation and the NF-κB Signaling Pathway in Hirschsprung Disease

2024-06-21

Abstract excerpt

Hirschsprung disease (HSCR, incidence 1/5000 live births) is caused by failure of neural crest-derived precursors to migrate, survive, proliferate or differentiate during the embryonic development of the Enteric Nervous System (ENS), which could be disrupted by many factors, in-cluding inflammatory processes. The NF-κB family controls several biological processes includ-ing inflammation, neurogenesis and cell migr...

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Literature Corpus work: 5628f558-05b2-5094-bf24-51a63c3e3830
DOI: 10.20944/preprints202406.1531.v1

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