Article

New L-proline uptake inhibitors with anti-Trypanosoma cruzi activity

2019-12-11

Abstract excerpt

L-Proline is an important amino acid for the pathogenic protists belonging to Trypanosoma and Leishmania genera. In Trypanosoma cruzi , the etiological agent of Chagas disease, this amino acid is involved in fundamental biological processes such as ATP production, differentiation of the insect and intracellular stages, the host cell infection and the resistance to a variety of stresses, including nutrition...

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Literature Corpus work: 49b8a528-32f9-5440-90ab-f261334a4d0b
DOI: 10.26434/chemrxiv.7564991.v2

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