Article

Extensive chemometric analysis exploring the acid-base equilibrium and self-association of unsymmetrical bisacridines reveals characteristics possibly relevant for their anticancer activity

2022-05-04

Abstract excerpt

<title>Abstract</title> <p>Unsymmetrical bisacridines (UAs), which represent a novel group of anticancer agents, were previously synthesized by our group. Our recent studies have shown high antitumor potential of UAs against multiple cancer cell lines and human tumor xenografts in nude mice. At the cellular level, they affected 3D cancer spheroid growth and their cellular uptake was selectively modulated by quant...

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Literature Corpus work: 3aba1786-00c2-527e-a0bd-bf6cfa735677
DOI: 10.21203/rs.3.rs-1579934/v1

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