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Mechanisms of human papillomavirus and host gene transcriptional deregulation in cervical carcinogenesis

2017-01-01

Abstract excerpt

Cervical malignancy is the fourth most common cause of cancer-related mortality in women worldwide; infection with high-risk human papillomavirus (HRHPV) is responsible for over 500,000 cases of cervical carcinoma each year, approximately 90% of which are squamous cell carcinomas (SCCs). Over half of all HPV-positive cervical SCCs are caused by the deregulated expression of HPV16 oncogenes E6 and E7 in proliferati...

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Literature Corpus work
24ada393-89af-5040-92ed-28e30a1d30f2
DOI
10.17863/cam.17098
Open publication

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