Back to search

Article

A conserved D/E-P motif in the nucleotide binding domain of plant ABCB/PGP-type ABC transporters defines their auxin transport capacity

2020-05-09

Abstract excerpt

Auxin transport activity of ABCB1 was suggested to be regulated by physical interaction with the FKBP42/Twisted Dwarf1 (TWD1), a bona fide peptidylprolyl cis-trans isomerase (PPIase), but all attempts to demonstrate such a PPIase activity on TWD1 have failed so far. By using a structure-based approach we have identified a series of surface-exposed proline residues in the C-terminal nucleotide binding fold and l...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1e2880d1-bb28-51cb-a03f-f5bb16441a87
DOI
10.1101/2020.05.08.084087
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A conserved D/E-P motif in the nucleotide binding domain of plant ABCB/PGP-type ABC transporters defines their auxin transport capacityDOI 10.1101/2020.05.08.084087
Expression of TWISTED DWARF1 lacking its in-plane membrane anchor leads to increased cell elongation and hypermorphic growth.Semantic proximity
Arabidopsis TWISTED DWARF1 functionally interacts with auxin exporter ABCB1 on the root plasma membrane.Semantic proximity
TWISTED DWARF1, a unique plasma membrane-anchored immunophilin-like protein, interacts with Arabidopsis multidrug resistance-like transporters AtPGP1 and AtPGP19.Semantic proximity
TWISTED DWARF 1 Associates with BRASSINOSTEROID-INSENSITIVE 1 to Regulate Early Events of the Brassinosteroid Signaling Pathway.Semantic proximity
Arabidopsis ABCB21 is a facultative auxin importer/exporter regulated by cytoplasmic auxin concentration.Semantic proximity
Structural and functional evolution of an auxin efflux carrier PIN1 and its functional characterization in common wheat.Semantic proximity
Immunophilin-like TWISTED DWARF1 modulates auxin efflux activities of Arabidopsis P-glycoproteins.Semantic proximity
Auxin transport: ABC proteins join the club.Semantic proximity
An apple a day: MdBPC2 transcription factor keeps the auxin away and causes dwarfing in Malus domestica.Semantic proximity
Mutational studies of the Aux/IAA proteins in Physcomitrella reveal novel insights into their function.Semantic proximity
Cross-species functional diversity within the PIN auxin efflux protein family.Semantic proximity
The ER-localized TWD1 immunophilin is necessary for localization of multidrug resistance-like proteins required for polar auxin transport in Arabidopsis roots.Semantic proximity
Select a neighboring publication to make it the new centre.