Article

Impact of In Vitro Cell Subculture on Mosaicism: Comparative Analysis of Chromosome Microarray and Karyotype Results

2023-10-19

Abstract excerpt

<title>Abstract</title> <p>Background Prenatal chromosomal abnormality detection traditionally relies on conventional karyotyping. This study explores the impact of in vitro cell subculture on prenatal diagnostic sample results, comparing cell subculture methods and chromosome microarray analysis (CMA). Methods We analyzed G-banding karyotyping data and CMA results from 2007 cases subjected to amniocentesis. This...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 011809d3-6b07-52ea-a05f-65f81f9914b5
DOI: 10.21203/rs.3.rs-3440949/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Impact of In Vitro Cell Subculture on Mosaicism: Comparative Analysis of Chromosome Microarray and Karyotype ResultsDOI 10.21203/rs.3.rs-3440949/v1Read

Fetal mosaicism, should conventional karyotype always be performed?Semantic proximity Read

Chromosomal mosaicism: Origins and clinical implications in preimplantation and prenatal diagnosisSemantic proximity Read

Proposed guidelines for diagnosis of chromosome mosaicism in amniocytes based on data derived from chromosome mosaicism and pseudomosaicism studiesSemantic proximity Read

Mosaic trisomy 2 at amniocentesis: Prenatal diagnosis and molecular genetic analysisSemantic proximity Read

Low-level mosaic trisomy 21 at amniocentesis in a pregnancy associated with cytogenetic discrepancy between cultured amniocytes and uncultured amniocytes, perinatal progressive decrease of the aneuploid cell line and a favorable fetal outcomeSemantic proximity Read

Prenatal diagnosis and molecular cytogenetic characterization of low-level true mosaicism for trisomy 21 using uncultured amniocytesSemantic proximity Read

Mosaic Trisomy 9 at Amniocentesis: Prenatal Diagnosis and Molecular Genetic AnalysesSemantic proximity Read

Prenatal diagnosis of mosaic trisomy 2: Discrepancy between molecular cytogenetic analyses of uncultured amniocytes and karyotyping of cultured amniocytes in a pregnancy with severe fetal intrauterine growth restrictionSemantic proximity Read

The difference between karyotype analysis and chromosome microarray for mosaicism of aneuploid chromosomes in prenatal diagnosisSemantic proximity Read

Mosaic trisomy 17 at amniocentesis: Prenatal diagnosis, molecular genetic analysis, and literature reviewSemantic proximity Read

Prenatal diagnosis of double autosomal mosaicism (47,XX,+8/47,XX,+14): phenotype and molecular cytogenetic analysis on different tissues.Semantic proximity Read

45,X/46,XX at amniocentesis associated with cytogenetic discrepancy between cultured amniocytes and uncultured amniocytes and in different amniocenteses and a favorable fetal outcome with a normal karyotype at birthSemantic proximity Read