Article
Genome-wide scan for CAG/CTG repeat expansions in Pimas with early onset of type 2 diabetes mellitus.
Molecular genetics and metabolism - 1 Jan 1999
Wolford J K, Bogardus C, Prochazka M
Abstract excerpt
The expansion of polymorphic CAG/CTG repeats in specific genes causes several neurodegenerative disorders and in many instances the length of the disease-causing repeat correlates with the onset age and/or severity of symptoms. Type 2 diabetes mellitus has features in common with diseases resulti...
Topics
- Age of Onset
- Alleles
- Arizona
- DNA
- Data Interpretation, Statistical
- Diabetes Mellitus, Type 2
- Gene Frequency
- Genetic Markers
- Genetic Testing
- Genome, Human
- Genotype
- Humans
- Indians, North American
- Pedigree
- Polymorphism, Genetic
- Trinucleotide Repeat Expansion
