Article
Modulation of nuclear localization of the influenza virus nucleoprotein through interaction with actin filaments.
Journal of virology - 1 Mar 1999
Digard P, Elton D, Bishop K, Medcalf E, Weeds A, Pope B
Abstract excerpt
The influenza virus genome is transcribed in the nuclei of infected cells but assembled into progeny virions in the cytoplasm. This is reflected in the cellular distribution of the virus nucleoprotein (NP), a protein which encapsidates genomic RNA to form ribonucleoprotein structures. At early ti...
Topics
- Actins
- Animals
- Cell Nucleus
- Cells, Cultured
- Cricetinae
- HeLa Cells
- Humans
- Mutation
- Nucleocapsid Proteins
- Nucleoproteins
- Orthomyxoviridae
- RNA, Viral
- Transcription, Genetic
- Viral Core Proteins