Article
New knowledge of genetic pathogenesis of hemochromatosis and Wilson's disease.
Advances in internal medicine - 1 Jan 1999
Bacon B R, Schilsky M L
Abstract excerpt
Discovery of the gene for WD has greatly enhanced our understanding of this disorder at the cellular level and has set the stage for future testing of new modes of therapy. Improvements in analytic methods for detecting mutations in genomic DNA will someday enable a rapid and cost-effective metho...
Topics
- Adenosine Triphosphatases
- Carrier Proteins
- Cation Transport Proteins
- Ceruloplasmin
- Copper
- Copper-Transporting ATPases
- Cost-Benefit Analysis
- DNA
- Hemochromatosis
- Hepatolenticular Degeneration
- Humans
- Liver
- Mass Screening
- Mutation