Article
Relationships between apolipoprotein(a) phenotype and increase of lipoprotein(a) by troglitazone.
Metabolism: clinical and experimental - 1 Jan 1999
Matsumoto K, Miyake S, Yano M, Ueki Y, Tominaga Y
Abstract excerpt
Troglitazone is a new oral hypoglycemic agent that reduces insulin resistance in non-insulin-dependent diabetes mellitus (NIDDM). However, this agent increases serum lipoprotein(a) [Lp(a)], which is known as an atherogenic lipoprotein. The relationships between the response of Lp(a) to troglitazone and the apolipoprotein(a) [apo(a)] phenotype were investigated in this study. Nineteen NIDDM patients were treated...
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