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PCR-restriction fragment length polymorphism (RFLP) analyses reveal both extensive clonality and local genetic differences in Candida albicans.

Molecular ecology - 1 Jan 1999

Xu J, Mitchell T G, Vilgalys R

Abstract excerpt

Using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method to obtain genotypes for the diploid pathogenic yeast, Candida albicans, we analysed 204 C. albicans isolates from three populations of the Duke University community: two from clinical sources [one from patients infected with human immunodeficiency virus (HIV) and the other from patients without HIV infection], and the...

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Identifiers

PMID: 9919698
DOI: 10.1046/j.1365-294x.1999.00523.x

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