Article
Quantification of hepatitis C virus RNA in serum by branched DNA-based signal amplification assays.
Journal of virological methods - 1 May 1999
Pawlotsky J M, Martinot-Peignoux M, Poveda J D, Bastie A, Le Breton V, Darthuy F, Rémiré J, Erlinger S, Dhumeaux D, Marcellin P
Abstract excerpt
The objective of the study was to compare the clinical sensitivity and specificity of versions 1.0 and 2.0 of the branched DNA (bDNA)-based hepatitis C virus (HCV) RNA quantification assay, and also to compare the values yielded by the two versions according to the HCV genotype. Serum samples from 268 patients tested routinely by a non-quantitative HCV RNA PCR assay (group A) were tested with version 2.0 of the...
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