The genetic and molecular mechanisms of motor neuron disease.

doi:10.1016/s0959-4388(98)80123-2

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Article

The genetic and molecular mechanisms of motor neuron disease.

Current opinion in neurobiology - 1 Dec 1998

Wong P C, Rothstein J D, Price D L

Abstract excerpt

Significant progress has been made in the identification of genes and chromosomal loci associated with several types of motor neuron disease. Of particular interest is recent work on the pathogenic mechanisms underlying these diseases, especially studies in in vitro model systems and in transgeni...

Topics

Amyotrophic Lateral Sclerosis
Animals
Humans
Mice
Mice, Transgenic
Motor Neuron Disease
Muscular Atrophy, Spinal
Mutation
Paraplegia
Superoxide Dismutase

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