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Article

Differential cell surface expression of the STRO-1 and alkaline phosphatase antigens on discrete developmental stages in primary cultures of human bone cells.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jan 1999

Gronthos S, Zannettino A C, Graves S E, Ohta S, Hay S J, Simmons P J

Abstract excerpt

Human osteoblast-like cells can be readily cultured from explants of trabecular bone, reproducibly expressing the characteristics of cells belonging to the osteoblastic lineage. Dual-color fluorescence-activated cell sorting was employed to develop a model of bone cell development in primary cultures of normal human bone cells (NHBCs) based on the cell surface expression of the stromal precursor cell marker...

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PMID: 9893065
DOI: 10.1359/jbmr.1999.14.1.47

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