Differential cell surface expression of the STRO-1 and alkaline phosphatase antigens on discrete developmental stages in primary cultures of human bone cells.

doi:10.1359/jbmr.1999.14.1.47

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Article

Differential cell surface expression of the STRO-1 and alkaline phosphatase antigens on discrete developmental stages in primary cultures of human bone cells.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jan 1999

Gronthos S, Zannettino A C, Graves S E, Ohta S, Hay S J, Simmons P J

Abstract excerpt

Human osteoblast-like cells can be readily cultured from explants of trabecular bone, reproducibly expressing the characteristics of cells belonging to the osteoblastic lineage. Dual-color fluorescence-activated cell sorting was employed to develop a model of bone cell development in primary cult...

Topics

Aged
Aged, 80 and over
Alkaline Phosphatase
Antibodies, Monoclonal
Antigens, Surface
Biomarkers
Bone Density
Bone Development
Bone Matrix
Cell Lineage
Cells, Cultured
Humans
Middle Aged
Osteogenesis
Phenotype

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PMID: 9893065
DOI: 10.1359/jbmr.1999.14.1.47

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9893065-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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