Article
Molecular characterization of HHV-8 positive primary effusion lymphoma reveals pathogenetic and histogenetic features of the disease.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 May 2000
Gaidano G, Capello D, Fassone L, Gloghini A, Cilia A M, Ariatti C, Buonaiuto D, Vivenza D, Gallicchio M, Avanzi G C, Prat M, Carbone A
Abstract excerpt
BACKGROUND: Primary effusion lymphoma (PEL) associates with HHV-8 infection, preferentially develops in immunodeficient patients and grows in the serous body cavities. PEL derives from post-germinal center, pre-terminally differentiated B-cells. The pathogenesis of PEL is unclear and the sole identified genetic lesions are human herpesvirus type-8 (HHV-8) infection in all cases and EBV infection in 70% of cases....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.