Article
[Characterization of the rpoB gene mutations in clinical isolates of rifampicin-resistant Mycobacterium tuberculosis].
Enfermedades infecciosas y microbiologia clinica - 1 Nov 1998
González N, Torres M J, Palomares J C, Aznar J
Abstract excerpt
OBJECTIVES: Characterization and frequency of the rpoB gene mutations associated with rifampin resistance in Mycobacterium tuberculosis clinical isolates in Sevilla. METHODS: Characterization of rpoB mutations in 21 rifampicin-resistant strains of M. tuberculosis isolated during a three-year peri...
Topics
- Amino Acid Substitution
- Bacterial Proteins
- DNA Mutational Analysis
- DNA, Bacterial
- DNA-Directed RNA Polymerases
- Drug Resistance, Microbial
- Genes, Bacterial
- Humans
- Mutation
- Mutation, Missense
- Mycobacterium tuberculosis
- Plant Proteins
- Polymorphism, Single-Stranded Conformational
- Rifampin
- Tuberculosis
- Tuberculosis, Multidrug-Resistant