Article
[Molecular pathogenesis and prognostic factors in testicular tumor].
Der Urologe. Ausg. A - 1 Nov 1998
Heidenreich A, Kuczyk M, Albers P
Abstract excerpt
Aim of this review article was to critically analyse the recently described zytogenetic and molecular markers for testicular germ cell tumors with regard to their clinical utility. The isochromosome i(12p) represents the most common and characteristic cytogenetic finding which already appears in testicular carcinoma in situ. A number of proto-oncogenes (Cyclin D and PTHLH) as well as putative tumor suppressor...
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