Article
Ionizing radiation and genetic risks. VI. Chronic multifactorial diseases: a review of epidemiological and genetical aspects of coronary heart disease, essential hypertension and diabetes mellitus.
Mutation research - 1 Jan 1999
Sankaranarayanan K, Chakraborty R, Boerwinkle E A
Abstract excerpt
This paper provides a broad overview of the epidemiological and genetical aspects of common multifactorial diseases in man with focus on three well-studied ones, namely, coronary heart disease (CHD), essential hypertension (EHYT) and diabetes mellitus (DM). In contrast to mendelian diseases, for which a mutant gene either in the heterozygous or homozygous condition is generally sufficient to cause disease, for...
Topics
- Chronic Disease
- Coronary Disease
- Diabetes Mellitus
- Family Health
- Female
- Genetic Predisposition to Disease
- Humans
- Hypertension
- Male
- Prevalence
- Radiation, Ionizing