Article
[Natural history of ovarian adenocarcinomas: from epidemiology to experimentation].
Contraception, fertilite, sexualite (1992) - 1 Nov 1998
Hamilton T C, Penault-Llorca F, Dauplat J
Abstract excerpt
The ovarian carcinogenesis is not well known because the diagnosis is usually delayed to an advanced stage with a lot of chromosomic abnormalities. On the other hand, there is a lack of animal models and preneoplastic patterns are discussed. Different ways of studying are in progress. Prophylactic oophorectomy in women with BRCA1 mutation provides ovaries that can be compared to a control group. Epithelial or...
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