Article
Endocrine withdrawal syndrome and its relevance to the management of hormone refractory prostate cancer.
European urology - 1 Jan 1998
Kelly W K
Abstract excerpt
Therapeutic options for patients with metastatic prostate cancer relapsing from primary hormonal therapy are limited. On the selective discontinuation of flutamide in patients that have relapsed on combined androgen ablation, a third of the patients will show a significant clinical benefit for 4-6 months. A multivariate model has identified prolonged exposure to combined androgen blockade, high baseline alkaline...
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