Article
The Munich vulnerability study on affective disorders: overview of the cross-sectional observations at index investigation.
Journal of psychiatric research - 1 Jan 2000
Lauer C J, Schreiber W, Modell S, Holsboer F, Krieg J C
Abstract excerpt
BACKGROUND: An altered nocturnal sleep pattern and a dysfunction of the hypothalamic-pituitary-adrenocortical system are neurobiological abnormalities typical for depression. A persistence of these neurobiological alterations during remission has been shown to be associated with an increased risk for a relapse. However, it remains unclear whether these persisting abnormalities are trait markers indicative of an...
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