Article
Differential development of umbilical and systemic arteries. II. Contractile proteins.
The American journal of physiology - 1 Jun 1998
Arens Y, Chapados R A, Cox B E, Kamm K E, Rosenfeld C R
Abstract excerpt
In fetal sheep, umbilical responsiveness to ANG II exceeds systemic vascular responsiveness. Fetal systemic vascular smooth muscle (VSM) exhibits an immature phenotype with decreased contractile protein contents, low 200-kDa myosin heavy chain (MHC) SM2, and significant nonmuscle MHC-B expression, whereas umbilical VSM phenotype is incompletely described. We tested the hypothesis that differences in vascular...
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