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Article

Role of NF-κB in immune and inflammatory responses in the gut

1 Dec 1998

Abstract excerpt

NF-kappaB is a pleiotropic transcription factor with key functions in the intestinal immune system. NF-kappaB family members control transcriptional activity of various promoters of proinflammatory cytokines, cell surface receptors, transcription factors, and adhesion molecules that are involved in intestinal inflammation. The perpetuated activation of NF-kappaB in patients with active inflammatory bowel disease...

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Identifiers

PMID: 9824616
DOI: 10.1136/gut.43.6.856

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