Article
Hereditary lymphedema: evidence for linkage and genetic heterogeneity.
Human molecular genetics - 1 Dec 1998
Ferrell R E, Levinson K L, Esman J H, Kimak M A, Lawrence E C, Barmada M M, Finegold D N
Abstract excerpt
Hereditary or primary lymphedema is a developmental disorder of the lymphatic system which leads to a disabling and disfiguring swelling of the extremities. Hereditary lymphedema generally shows an autosomal dominant pattern of inheritance with reduced penetrance, variable expression and variable age at onset. Three multigeneration families demonstrating the phenotype of hereditary lymphedema segregating as an...
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