Article
Multiple dideoxynucleoside analogue-resistant (MddNR) HIV-1 strains isolated from patients from different European countries.
AIDS (London, England) - 22 Oct 1998
Schmit J C, Van Laethem K, Ruiz L, Hermans P, Sprecher S, Sönnerborg A, Leal M, Harrer T, Clotet B, Arendt V, Lissen E, Witvrouw M, Desmyter J, De Clercq E, Vandamme A M
Abstract excerpt
OBJECTIVE: To study the prevalence of multiple dideoxynucleoside (ddN)-resistant (MddNR) HIV-1 in European patients under treatment with multiple ddN analogues, and to characterize MddNR strains genotypically and phenotypically. DESIGN AND METHODS: Blood samples from patients after > or = 6 month...
Topics
- Amino Acid Sequence
- Anti-HIV Agents
- Dideoxynucleosides
- Drug Resistance, Multiple
- Drug Therapy, Combination
- Europe
- HIV Infections
- HIV-1
- Humans
- Molecular Sequence Data
- Phenotype
- Reverse Transcriptase Inhibitors
- Sequence Homology, Amino Acid