Limb girdle muscular dystrophy type 2A (CAPN3): mapping using allelic association.

doi:10.1159/000022825

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Article

Limb girdle muscular dystrophy type 2A (CAPN3): mapping using allelic association.

Human heredity - 1 Jan 2000

Lonjou C, Collins A, Beckmann J, Allamand V, Morton N

Abstract excerpt

Recently a graphical study of linkage disequilibrium around the CAPN3 locus failed to refine the 1.3-Mb interval suggested by haplotype sharing. On the contrary, the Malecot model as implemented in the ALLASS program maps CAPN3 within 3 kb of its true location (23 kb from the locus midpoint), ove...

Topics

Alleles
Calpain
Genes, Recessive
Genetic Markers
Humans
Isoenzymes
Linkage Disequilibrium
Models, Genetic
Muscle Proteins
Muscular Dystrophies
Peptide Fragments

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