Increased activity of wall hydrolytic enzymes may explain the phenotype of Saccharomyces cerevisiae fragile mutants.

Abstract excerpt

Fragile mutants of Saccharomyces cerevisiae require osmotic stabilizers and lyse in hypotonic solutions. A single recessive mutation, srb1, is responsible for their phenotype, but the cause of cell lysis remains uncertain. We have analyzed three possible mechanisms for this behavior: comparative amounts of wall per cell; their chitin content; and the relative activity of wall hydrolytic enzymes activated by...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Wall
• Share to Chitin
• Share to Mutation