Article
[Clinical value of gene diagnosis in breast cancer].
Rinsho byori. The Japanese journal of clinical pathology - 1 Sept 1998
Iwase H
Abstract excerpt
Gene diagnosis has been mainly performed for three purposes, 1) to assess the prophylactic risk from genetic alterations of candidate gene, 2) to confirm the diagnosis from a small volume of cancer cells using polymerase chain reaction method and 3) to understand the biological characteristic of the tumor by assessing genetic instabilities. BRCA1 and BRCA2 are quite important candidate genes in familial breast...
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