Article
[Clinical value of gene diagnosis in breast cancer].
Rinsho byori. The Japanese journal of clinical pathology - 1 Sept 1998
Iwase H
Abstract excerpt
Gene diagnosis has been mainly performed for three purposes, 1) to assess the prophylactic risk from genetic alterations of candidate gene, 2) to confirm the diagnosis from a small volume of cancer cells using polymerase chain reaction method and 3) to understand the biological characteristic of...
Topics
- Breast Neoplasms
- Female
- Gene Expression Regulation, Neoplastic
- Genes, BRCA1
- Genes, Tumor Suppressor
- Genes, erbB-2
- Genes, p53
- Heterozygote
- Humans
- Loss of Heterozygosity
- Lymphatic Metastasis
- Microsatellite Repeats
- Mutation
- Reverse Transcriptase Polymerase Chain Reaction