Conformational alterations resulting from mutations in cytoplasmic domains of the alpha subunit of the Na,K-ATPase.

Article

Conformational alterations resulting from mutations in cytoplasmic domains of the alpha subunit of the Na,K-ATPase.

Acta physiologica Scandinavica. Supplementum - 1 Aug 1998

Blostein R, Daly S E, Boxenbaum N, Lane L K, Arguello J M, Lingrel J B, Karlish S J, Caplan M J, Dunbar L

Abstract excerpt

This paper summarizes experiments concerned with the functional consequences of mutations in cytoplasmic regions of the alpha 1 subunit of the Na,K-ATPase, in particular the amino terminus, the first cytoplasmic loop between transmembrane segments M2 and M3, and the major cytoplasmic loop between...

Topics

Amino Acid Substitution
Cytoplasm
Isoenzymes
Mutation
Protein Conformation
Sodium-Potassium-Exchanging ATPase

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.