Article
Phenytoin alters transcript levels of hormone-sensitive lipase in muscle from horses with hyperkalemic periodic paralysis.
Archives of biochemistry and biophysics - 15 Oct 1998
Yudkowsky M L, Beech J, Fletcher J E
Abstract excerpt
In equine hyperkalemic periodic paralysis (HyperPP), there is evidence suggesting that the primary defect in the sodium channel is associated with a secondary alteration in triacylglycerol-associated fatty acid metabolism (TAFAM) in skeletal muscle. Furthermore, TAFAM may be involved in the thera...
Topics
- Animals
- Carnitine O-Palmitoyltransferase
- Carrier Proteins
- Cells, Cultured
- Fatty Acid-Binding Proteins
- Fatty Acids
- Genotype
- Horse Diseases
- Horses
- Hyperkalemia
- Muscle, Skeletal
- Myelin P2 Protein
- Neoplasm Proteins
- Paralyses, Familial Periodic
- Phenytoin
- RNA, Messenger
- Sodium Channels
- Sterol Esterase